BAMBI Antibodies

Target Information

BAMBI (BMP and activin membrane-bound inhibitor homolog, NMA) is a membrane spanning glycoprotein that acts as a negative regulator of TGF-beta signaling during development. BAMBI transcription regulation is under the influence of beta-catenin, BMP, smad3 and smad4. BAMBI expression can increase in colorectal and hepatocellular carcinomas relative to non-cancerous tissues. BAMBI is expressed at high levels during odontogenesis. BAMBI is coexpressed with Bmp-4 during early Xenopus embryogenesis and can be detected in poorly metastatic human melanoma cell lines.

Synonyms

2610003H06Rik; BAMBI; BMP and activin membrane bound inhibitor; BMP and activin membrane-bound inhibitor; BMP and activin membrane-bound inhibitor homolog; BMP and activin membrane-bound inhibitor, homolog; kinase-deficient TGFbeta superfamily receptor subunit; NMA; Non-metastatic gene A protein; putative transmembrane protein NMA