DTX3 Proteins

Protein Information

Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context. Functions as an ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.

Synonyms

deltex 3 homolog (Drosophila); deltex 3, E3 ubiquitin ligase; deltex E3 ubiquitin ligase 3; deltex homolog 3; Deltex3; DTX3; FLJ34766; mDTX3; mg310; MGC138863; MGC138864; Probable E3 ubiquitin-protein ligase DTX3; protein deltex-3; RING finger protein 154; RING-type E3 ubiquitin transferase DTX3; RNF154