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Invitrogen
Human DTX3 (aa 149-202) Control Fragment Recombinant Protein
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Product Details
RP-101968
Species
Expression System
Amino acid sequence
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Type
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Conjugate
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Purification
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Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (96%), Rat (96%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-63762. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context. Functions as an ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: deltex 3, E3 ubiquitin ligase; deltex homolog 3; Deltex3; FLJ34766; MGC138863; MGC138864; Probable E3 ubiquitin-protein ligase DTX3; Protein deltex-3; RING finger protein 154; RING-type E3 ubiquitin transferase DTX3
Gene Aliases: deltex3; DTX3; RNF154
UniProt ID: (Human) Q8N9I9
Entrez Gene ID: (Human) 196403
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