DNAH5 Proteins

Protein Information

This gene encodes a dynein protein, which is part of a microtubule-associated motor protein complex consisting of heavy, light, and intermediate chains. This protein is an axonemal heavy chain dynein. It functions as a force-generating protein with ATPase activity, whereby the release of ADP is thought to produce the force-producing power stroke. Mutations in this gene cause primary ciliary dyskinesia type 3, as well as Kartagener syndrome, which are both diseases due to ciliary defects.

Synonyms

Axonemal beta dynein heavy chain 5; CILD3; Ciliary dynein heavy chain 5; DNAH5; DNAHC5; dynein axonemal heavy chain 5; dynein heavy chain 5, axonemal; dynein, axonemal, heavy chain 5; dynein, axonemal, heavy polypeptide 5; HL1; KIAA1603; KTGNR; PCD