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Invitrogen
Human DNAH5 (aa 54-142) Control Fragment Recombinant Protein
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Product Details
RP-96796
Species
Expression System
Amino acid sequence
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Class
Type
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Conjugate
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Purification
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Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (83%), Rat (83%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-57958. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
This gene encodes a dynein protein, which is part of a microtubule-associated motor protein complex consisting of heavy, light, and intermediate chains. This protein is an axonemal heavy chain dynein. It functions as a force-generating protein with ATPase activity, whereby the release of ADP is thought to produce the force-producing power stroke. Mutations in this gene cause primary ciliary dyskinesia type 3, as well as Kartagener syndrome, which are both diseases due to ciliary defects.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: Axonemal beta dynein heavy chain 5; Ciliary dynein heavy chain 5; Dynein axonemal heavy chain 5; dynein, axonemal, heavy chain 5; dynein, axonemal, heavy polypeptide 5
Gene Aliases: CILD3; DNAH5; DNAHC5; HL1; KIAA1603; KTGNR; PCD
UniProt ID: (Human) Q8TE73
Entrez Gene ID: (Human) 1767
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