CLYBL Proteins

Protein Information

CLYBL, also named as CLB, is a Mitochondrial citramalyl-CoA lyase indirectly involved in the vitamin B12 metabolism. It is a human mitochondrial enzyme of unknown function that is found in multiple eukaryotic taxa and conserved to bacteria. It acts as a beta-methylmalate synthase in vitro, by mediating conversion of glyoxylate and propionyl-CoA to beta-methylmalate. There are two isoforms with MW 31-33 kDa and 35-37 kDa.

Synonyms

(3S)-malyl-CoA thioesterase; 0610033J05Rik; 2310014M14Rik; AI256068; bA134O15.1; Beta-methylmalate synthase; Citramalyl-CoA lyase, mitochondrial; citrate lyase beta like; citrate lyase beta-like; Citrate lyase subunit beta-like protein; Citrate lyase subunit beta-like protein, mitochondrial; Clb; Clybl; malate synthase