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Invitrogen
Human CLYBL (aa 34-115) Control Fragment Recombinant Protein
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Product Details
RP-97958
Species
Expression System
Amino acid sequence
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Conjugate
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Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (88%), Rat (88%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-59251. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
CLYBL, also named as CLB, is a Mitochondrial citramalyl-CoA lyase indirectly involved in the vitamin B12 metabolism. It is a human mitochondrial enzyme of unknown function that is found in multiple eukaryotic taxa and conserved to bacteria. It acts as a beta-methylmalate synthase in vitro, by mediating conversion of glyoxylate and propionyl-CoA to beta-methylmalate. There are two isoforms with MW 31-33 kDa and 35-37 kDa.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: (3S)-malyl-CoA thioesterase; bA134O15.1; Beta-methylmalate synthase; Citramalyl-CoA lyase, mitochondrial; Citrate lyase beta-like; Citrate lyase subunit beta-like protein; Malate synthase
Gene Aliases: CLB; CLYBL
UniProt ID: (Human) Q8N0X4
Entrez Gene ID: (Human) 171425
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