CCDC105 Proteins

Protein Information

CCDC105 (Coiled-Coil Domain-Containing 105) is a gene that encodes a protein involved in various cellular processes, primarily associated with the structure and function of centrioles and cilia. The CCDC105 protein contains coiled-coil domains that facilitate protein-protein interactions, crucial for the assembly and stabilization of microtubule structures within cells. Studies indicate that CCDC105 plays a key role in ciliogenesis, the process by which cells form cilia, which are essential for cell motility, fluid movement, and signal transduction. Dysregulation or mutations in CCDC105 have been implicated in ciliopathies, a group of disorders arising from defective cilia, leading to symptoms such as respiratory issues, kidney disease, and developmental abnormalities. Research continues to explore the specific molecular mechanisms by which CCDC105 influences ciliary dynamics and its broader implications in human health and disease.

Synonyms

CCDC105; coiled-coil domain containing 105; Coiled-coil domain-containing protein 105