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OriGene
CLNS1A Polyclonal Antibody
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FIGURE: 1 / 1
CLNS1A Antibody (TA590737) in WB
Product Details
TA590737
Species Reactivity
Host/Isotype
Class
Type
Immunogen
Conjugate
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Purification
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Target Information
Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. PcG proteins are not required to initiate repression, but to maintain it during later stages of development. They probably act via methylation of histones, rendering chromatin heritably changed in its expressibility. Involved in transcriptional regulation mediated by ligand-bound nuclear hormone receptors, such as peroxisome proliferator-activated receptor gamma (PPARG). Acts as coactivator for PPARG and enhances its adipocyte differentiation-inducing activity; the function seems to involve differential recruitment of acetylated and methylated histone H3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: ARPC1A; chloride channel regulatory protein; Chloride channel, nucleotide sensitive 1A; chloride channel, nucleotide-sensitive, 1A; Chloride conductance regulatory protein ICln; Chloride ion current inducer protein; ClCI; I(Cln); Methylosome subunit pICln; Reticulocyte pICln; reticulocyte protein ICln; SOP2-like protein; SOP2L
Gene Aliases: CLCI; CLNS1A; CLNS1B; ICLN
UniProt ID: (Human) P54105
Entrez Gene ID: (Human) 1207
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