CLNS1A Antibodies

Target Information

Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. PcG proteins are not required to initiate repression, but to maintain it during later stages of development. They probably act via methylation of histones, rendering chromatin heritably changed in its expressibility. Involved in transcriptional regulation mediated by ligand-bound nuclear hormone receptors, such as peroxisome proliferator-activated receptor gamma (PPARG). Acts as coactivator for PPARG and enhances its adipocyte differentiation-inducing activity; the function seems to involve differential recruitment of acetylated and methylated histone H3.

Synonyms

2610036D06Rik; 2610100O04Rik; ARPC1A; chloride channel current inducer; chloride channel regulator; chloride channel regulatory protein; chloride channel, nucleotide sensitive 1A; chloride channel, nucleotide-sensitive, 1A; chloride conductance regulatory protein ICln; Chloride ion current inducer protein; chloride nucleotide-sensitive channel 1A; ClCI; Clcni; Clns 1a; Clns1a; CLNS1B; I(Cln); Icln; Methylosome subunit pICln; pICln; Rcl1; Reticulocyte pICln; reticulocyte protein ICln; SOP2L; SOP2-like protein