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  • TSN Antibodies

OriGene

TSN Monoclonal Antibody (OTI1B5), TrueMAB™

View all (14) TSN antibodies

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Datasheet
Protocols
Questions & Answers

Cite TSN Monoclonal Antibody (OTI1B5), TrueMAB™

  • Antibody Testing Data (6)
TSN Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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TSN Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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FIGURE: 1 / 6

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TSN Antibody (CF809099) in IHC (P)

Immunohistochemical staining of paraffin-embedded human tonsil within the normal limits using anti-TSN mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer (pH8.5) at 120°C for 3 min, TA809099)(1:500). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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TSN Antibody in Immunohistochemistry (Paraffin) (IHC (P))
TSN Antibody in Immunohistochemistry (Paraffin) (IHC (P))
TSN Antibody in Immunohistochemistry (Paraffin) (IHC (P))
TSN Antibody in Immunohistochemistry (Paraffin) (IHC (P))
TSN Antibody in Western Blot (WB)
TSN Antibody in Western Blot (WB)
TSN Monoclonal Antibody (OTI1B5), TrueMAB™

Product Details

CF809099

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:2,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:500
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Mouse / IgG2a

Class

Monoclonal

Type

Antibody

Clone

OTI1B5

Immunogen

Human recombinant protein fragment corresponding to amino acids 1-51 of human TSN produced in E.coli.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.3, with 8% trehalose

Contains

no preservative

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)

Target Information

Translin is a DNA-binding protein which specifically recognizes conserved target sequences at the breakpoint junction of chromosomal translocations. Translin polypeptides form a multimeric structure that is responsible for its DNA-binding activity. Recombination-associated motifs and translin-binding sites are present at recombination hotspots and may serve as indicators of breakpoints in genes which are fused by translocations. These binding activities may play a crucial role in chromosomal translocation in lymphoid neoplasms. Recent evidence suggests that in combination with a binding partner Trax, Translin binds RNA and mediates trafficking in neurons.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: C3PO; Component 3 of promoter of RISC; recombination hotspot associated factor; recombination hotspot-binding protein; TB-RBP; testis brain-RNA binding protein; Testis/brain RNA-binding protein; testis/brain-RNA-binding protein; Translin

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Gene Aliases: 2610034C24Rik; AU040286; BCLF-1; C3PO; RCHF1; REHF-1; TB-RBP; TBRBP; TRSLN; TSN

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UniProt ID: (Human) Q15631, (Mouse) Q62348

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Entrez Gene ID: (Human) 7247, (Rat) 60381, (Mouse) 22099

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Function(s)
DNA binding mRNA binding endonuclease activity protein binding sequence-specific DNA binding single-stranded DNA binding RNA binding endoribonuclease activity protein complex binding nuclease activity hydrolase activity phosphoric ester hydrolase activity T/G mismatch-specific endonuclease activity retroviral 3' processing activity
Process(es)
DNA recombination gene silencing by RNA nucleic acid phosphodiester bond hydrolysis RNA phosphodiester bond hydrolysis, endonucleolytic
It has to be done as per old AB suggested Products section.
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