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Invitrogen
Bcl-W Polyclonal Antibody
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Product Details
PA5-101328
Species Reactivity
Host/Isotype
Class
Type
Immunogen
Conjugate
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Concentration
Purification
Storage buffer
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RRID
Product Specific Information
Antibody detects endogenous levels of total BCL2L2.
Target Information
Using a PCR-based strategy, an additional protein with life-promoting activity, designated Bcl-w, has been identified. The protein is highly conserved between mouse and human and is encoded by a gene located near the TCRalpha gene on chromosome 14. Bcl-w is expressed in myeloid cell lines but not in T and B lymphocytes, and can be found in a wide range of tissues. An alternative splicing event in exon 4 results in two transcripts. The first, Bcl-w, encodes a protein of 193 amino acids, and the second, Bcl-w/rox, encodes a protein 333 amino acids in length. The "rox" portion of Bcl-w/rox shows a striking 66% amino acid sequence identity with the Drosophila rox2 protein; however, the Bcl-w/rox transcript may be expressed at very low levels.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: Apoptosis regulator Bcl-W; Bcl-2-like protein 2; Bcl2-L-2; BCL2-like 2 protein; Bcl2-like protein 2; c98; protein phosphatase 1, regulatory subunit 51
Gene Aliases: AW048834; BCL-W; BCL-WEL; BCL-WS; BCL2-L-2; BCL2L2; BCLW; c98; Gtrgal2; Gtrosa41; KIAA0271; PPP1R51
UniProt ID: (Human) Q92843, (Mouse) P70345
Entrez Gene ID: (Human) 599, (Mouse) 12050, (Rat) 60434
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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