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NeoBiotechnologies

BCL2-like 2 Monoclonal Antibody (CPTC-BCL2L2-2)

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Datasheet
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Questions & Answers

Cite BCL2-like 2 Monoclonal Antibody (CPTC-BCL2L2-2)

  • Antibody Testing Data (3)
BCL2-like 2 Antibody in Western Blot (WB)
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BCL2-like 2 Antibody in Western Blot (WB)
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FIGURE: 1 / 3

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BCL2-like 2 Antibody (599-MSM1-P0) in WB

Western blot analysis of PC-3, HEK293, MCF-7, HEPG2 and U87 cells. BCL2L2 Mouse Monoclonal Antibody (CPTC-BCL2L2-2). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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BCL2-like 2 Antibody in Western Blot (WB)
BCL2-like 2 Antibody in Peptide array (ARRAY)
BCL2-like 2 Antibody in SDS-PAGE (SDS-PAGE)
BCL2-like 2 Monoclonal Antibody (CPTC-BCL2L2-2)

Product Details

599-MSM1-P0

Applications
Tested Dilution
Publications

Western Blot (WB)

1-2 µg/mL
-

ELISA (ELISA)

Assay-dependent
-

Peptide Array (Array)

Assay-dependent
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

CPTC-BCL2L2-2

Immunogen

Recombinant human full-length BCL2L2 protein
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

200 µg/mL

Purification

Protein A/G

Storage buffer

PBS, pH 7.4, with 0.05% BSA

Contains

0.05% sodium azide

Storage conditions

4°C, do not freeze

Shipping conditions

Wet ice

Target Information

Using a PCR-based strategy, an additional protein with life-promoting activity, designated Bcl-w, has been identified. The protein is highly conserved between mouse and human and is encoded by a gene located near the TCRalpha gene on chromosome 14. Bcl-w is expressed in myeloid cell lines but not in T and B lymphocytes, and can be found in a wide range of tissues. An alternative splicing event in exon 4 results in two transcripts. The first, Bcl-w, encodes a protein of 193 amino acids, and the second, Bcl-w/rox, encodes a protein 333 amino acids in length. The "rox" portion of Bcl-w/rox shows a striking 66% amino acid sequence identity with the Drosophila rox2 protein; however, the Bcl-w/rox transcript may be expressed at very low levels.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Apoptosis regulator Bcl-W; Bcl-2-like protein 2; Bcl2-L-2; BCL2-like 2 protein; Bcl2-like protein 2; protein phosphatase 1, regulatory subunit 51

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Gene Aliases: BCL-W; BCL2-L-2; BCL2L2; BCLW; KIAA0271; PPP1R51

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UniProt ID: (Human) Q92843

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Entrez Gene ID: (Human) 599

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Function(s)
protein binding protein homodimerization activity protein heterodimerization activity BH domain binding
Process(es)
spermatogenesis intrinsic apoptotic signaling pathway in response to DNA damage negative regulation of apoptotic process Sertoli cell proliferation extrinsic apoptotic signaling pathway in absence of ligand negative regulation of intrinsic apoptotic signaling pathway
It has to be done as per old AB suggested Products section.
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