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See other CXCL8 GE Assays ›
Gene Symbol:
CXCL8
Gene Name:
C-X-C motif chemokine ligand 8
Gene Aliases:
GCP-1, GCP1, IL8, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1
Chromosome Location:
Chr.4: 73740506 - 73743716 on Build GRCh38
Species:
Human
Species Specific ID (Flybase ID):
-
Assay ID Hs00174103_m1
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Catalog # 4331182
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  • Genomic Map
  • Assay Details
  • More Information
  • Citations (86)

Genomic Map

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Assay Details

Gene Symbol: CXCL8
Interrogated Sequence Translated Protein Exon Boundary Assay Location IMAGE Clone ID Amplicon Length
RefSeq NM_000584.3 NP_000575.1 1 - 2 222 101
GenBank mRNA AK131067.1 - 1 - 2 159 101
AK311874.1 - 1 - 2 159 101
BC013615.1 - 1 - 2 109 3882471 101
BG497712.1 - 1 - 2 223 101
BT007067.1 - 1 - 2 69 101
CR542151.1 - 1 - 2 69 101
M17017.1 - 1 - 2 159 101
M26383.1 - 1 - 2 143 101
Y00787.1 - 1 - 2 170 101
Z11686.1 - 1 - 2 69 101

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More Information


Set Membership:

Ambion siRNA available Amplicon length greater than or equal to 101 Immune Tolerance Network Mammalian Gene Collection Recommended Assay Homo sapiens Human Androgen Panel Human Chemokine Panel Human Immune Response Human NFkB Pathway Human Angiogenesis Inventoried MicroArray Quality Control (MAQC) Human_Immune Human_Nfkb Human_Angiogenesis Human_Androgen Human_Chemokine Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene CXCL8

Panther Classification:

Molecular Function -

chemokine

Gene Ontology Categories:

Function(s) Process(es)

angiogenesis
response to molecule of bacterial origin
movement of cell or subcellular component
chemotaxis
inflammatory response
immune response
cell cycle arrest
signal transduction
G-protein coupled receptor signaling pathway
negative regulation of cell proliferation
calcium-mediated signaling
regulation of cell adhesion
neutrophil chemotaxis
receptor internalization
response to endoplasmic reticulum stress
intracellular signal transduction
PERK-mediated unfolded protein response
neutrophil activation
cellular response to fibroblast growth factor stimulus
regulation of single stranded viral RNA replication via double stranded DNA intermediate
negative regulation of G-protein coupled receptor protein signaling pathway
positive regulation of angiogenesis
embryonic digestive tract development
induction of positive chemotaxis
chemokine-mediated signaling pathway
cellular response to lipopolysaccharide
cellular response to interleukin-1
cellular response to tumor necrosis factor
positive regulation of neutrophil chemotaxis
interleukin-8 receptor binding
protein binding
chemokine activity

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Citations (86)

IFN-gamma impairs release of IL-8 by IL-1beta-stimulated A549 lung carcinoma cells.
Authors
Boost KA, Sadik CD, Bachmann M, Zwissler B, Pfeilschifter J, Muhl H
Journal
Bmc Cancer - Page No 265 (Tue Jan 01 00:00:00 UTC 2008)
Volume (Year)
8 (2008)
Product Usage
-
Norepinephrine upregulates VEGF, IL-8, and IL-6 expression in human melanoma tumor cell lines: implications for stress-related enhancement of tumor progression.
Authors
Yang EV, Kim SJ, Donovan EL, Chen M, Gross AC, Webster Marketon JI, Barsky SH, Glaser R
Journal
Brain Behav Immun - Page No 267 (Sun Feb 01 00:00:00 UTC 2009)
Volume (Year)
23 (2009)
Product Usage
-
The synthetic liver X receptor agonist GW3965 reduces tissue factor production and inflammatory responses in human islets in vitro.
Authors
Scholz H, Lund T, Dahle MK, Collins JL, Korsgren O, Wang JE, Foss A
Journal
Diabetologia - Page No 1352 (Wed Jul 01 00:00:00 UTC 2009)
Volume (Year)
52 (2009)
Product Usage
-
Role of hypoxia-inducible factor-1alpha in hypoxia-induced expressions of IL-8, MMP-1 and MMP-3 in rheumatoid fibroblast-like synoviocytes.
Authors
Ahn JK, Koh EM, Cha HS, Lee YS, Kim J, Bae EK, Ahn KS
Journal
Rheumatology (Oxford) - Page No 834 (Sun Jun 01 00:00:00 UTC 2008)
Volume (Year)
47 (2008)
Product Usage
-
Intrinsic renal cell and leukocyte-derived TLR4 aggravate experimental anti-MPO glomerulonephritis.
Authors
Summers SA, van der Veen BS, O'Sullivan KM, Gan PY, Ooi JD, Heeringa P, Satchell SC, Mathieson PW, Saleem MA, Visvanathan K, Holdsworth SR, Kitching AR
Journal
Kidney Int - Page No 1263 (Wed Dec 01 00:00:00 UTC 2010)
Volume (Year)
78 (2010)
Product Usage
-
Reversal of gene expression changes in the colorectal normal-adenoma pathway by NS398 selective COX2 inhibitor.
Authors
Galamb O, Spisak S, Sipos F, Toth K, Solymosi N, Wichmann B, Krenacs T, Valcz G, Tulassay Z, Molnar B
Journal
Br J Cancer - Page No 765 (Tue Feb 16 00:00:00 UTC 2010)
Volume (Year)
102 (2010)
Product Usage
-
NSAID-induced antral ulcers are associated with distinct changes in mucosal gene expression.
Authors
Desai JC, Goo T, Fukata M, Sanyal S, Dikman A, Miller K, Cohen L, Brooks A, Wang Q, Abreu MT, Aisenberg J
Journal
Aliment Pharmacol Ther - Page No 71 (Wed Jul 01 00:00:00 UTC 2009)
Volume (Year)
30 (2009)
Product Usage
-
The Human Cutaneous Squamous Cell Carcinoma Microenvironment Is Characterized by Increased Lymphatic Density and Enhanced Expression of Macrophage-Derived VEGF-C.
Authors
Moussai D, Mitsui H, Pettersen JS, Pierson KC, Shah KR, Suarez-Farinas M, Cardinale IR, Bluth MJ, Krueger JG, Carucci JA
Journal
J Invest Dermatol - Page No (Thu Sep 09 00:00:00 UTC 2010)
Volume (Year)
 (2010)
Product Usage
-
Iodide-induced chemokines and genes related to immunological function in cultured human thyroid follicles in the presence of thyrotropin.
Authors
Yamazaki K, Tanigawa K, Suzuki K, Yamada E, Yamada T, Takano K, Obara T, Sato K
Journal
Thyroid - Page No 67 (Fri Jan 01 00:00:00 UTC 2010)
Volume (Year)
20 (2010)
Product Usage
-
Olive oil-based lipid emulsion's neutral effects on neutrophil functions and leukocyte-endothelial cell interactions.
Authors
Buenestado A, Cortijo J, Sanz MJ, Naim-Abu-Nabah Y, Martinez-Losa M, Mata M, Issekutz AC, Marti-Bonmati E, Morcillo EJ
Journal
Jpen J Parenter Enteral Nutr - Page No 286 (Sat Jul 01 00:00:00 UTC 2006)
Volume (Year)
30 (2006)
Product Usage
-
Epigenetic inactivation of RASSF2 in oral squamous cell carcinoma.
Authors
Imai T, Toyota M, Suzuki H, Akino K, Ogi K, Sogabe Y, Kashima L, Maruyama R, Nojima M, Mita H, Sasaki Y, Itoh F, Imai K, Shinomura Y, Hiratsuka H, Tokino T
Journal
Cancer Sci - Page No 958 (Thu May 01 00:00:00 UTC 2008)
Volume (Year)
99 (2008)
Product Usage
-
IL-1-induced post-transcriptional mechanisms target overlapping translational silencing and destabilizing elements in IkappaBzeta mRNA.
Authors
Dhamija S, Doerrie A, Winzen R, Dittrich-Breiholz O, Taghipour A, Kuehne N, Kracht M, Holtmann H
Journal
J Biol Chem - Page No 29165 (Fri Sep 17 00:00:00 UTC 2010)
Volume (Year)
285 (2010)
Product Usage
-
Pattern recognition receptors and interleukin-8 mediate effects of Gram-positive and Gram-negative bacteria on lung epithelial cell function.
Authors
Sorrentino R, de Souza PM, Sriskandan S, Duffin C, Paul-Clark MJ, Mitchell JA
Journal
Br J Pharmacol - Page No 864 (Sun Jun 01 00:00:00 UTC 2008)
Volume (Year)
154 (2008)
Product Usage
-
Calcium dependent and independent cytokine synthesis by air pollution particle-exposed human bronchial epithelial cells.
Authors
Sakamoto N, Hayashi S, Gosselink J, Ishii H, Ishimatsu Y, Mukae H, Hogg JC, van Eeden SF
Journal
Toxicol Appl Pharmacol - Page No 134 (Sat Dec 01 00:00:00 UTC 2007)
Volume (Year)
225 (2007)
Product Usage
-
Tissue Factor-Factor VIIa complex induces cytokine expression in coronary artery smooth muscle cells.
Authors
Demetz G, Seitz I, Stein A, Steppich B, Groha P, Brandl R, Schomig A, Ott I
Journal
Atherosclerosis - Page No 466 (Fri Oct 01 00:00:00 UTC 2010)
Volume (Year)
212 (2010)
Product Usage
-
Alterations in intestinal fatty acid metabolism in inflammatory bowel disease.
Authors
Heimerl S, Moehle C, Zahn A, Boettcher A, Stremmel W, Langmann T, Schmitz G
Journal
Biochim Biophys Acta - Page No 341 (Wed Mar 01 00:00:00 UTC 2006)
Volume (Year)
1762 (2006)
Product Usage
-
Induction of neutrophil gelatinase-associated lipocalin expression by co-stimulation with interleukin-17 and tumor necrosis factor-alpha is controlled by IkappaB-zeta but neither by C/EBP-beta nor C/EBP-delta.
Authors
Karlsen JR, Borregaard N, Cowland JB
Journal
J Biol Chem - Page No 14088 (Fri May 07 00:00:00 UTC 2010)
Volume (Year)
285 (2010)
Product Usage
-
Gene expression profiles in psoriasis: analysis of impact of body site location and clinical severity.
Authors
Quekenborn-Trinquet V, Fogel P, Aldana-Jammayrac O, Ancian P, Demarchez M, Rossio P, Richards HL, Kirby B, Nguyen C, Voegel JJ, Griffiths CE
Journal
Br J Dermatol - Page No 489 (Tue Mar 01 00:00:00 UTC 2005)
Volume (Year)
152 (2005)
Product Usage
-
Role of Aspergillus fumigatus DvrA in host cell interactions and virulence.
Authors
Ejzykowicz DE, Solis NV, Gravelat FN, Chabot J, Li X, Sheppard DC, Filler SG
Journal
Eukaryot Cell - Page No 1432 (Fri Oct 01 00:00:00 UTC 2010)
Volume (Year)
9 (2010)
Product Usage
-
N(epsilon)-carboxymethyllysine-modified proteins are unable to bind to RAGE and activate an inflammatory response.
Authors
Buetler TM, Leclerc E, Baumeyer A, Latado H, Newell J, Adolfsson O, Parisod V, Richoz J, Maurer S, Foata F, Piguet D, Junod S, Heizmann CW, Delatour T
Journal
Mol Nutr Food Res - Page No 370 (Sat Mar 01 00:00:00 UTC 2008)
Volume (Year)
52 (2008)
Product Usage
-
Inhibition of 13-cis retinoic acid-induced gene expression of homeobox B7 by thalidomide.
Authors
Milanovic D, Maier P, Lohr F, Wenz F, Herskind C
Journal
Int J Cancer - Page No 1205 (Sat Sep 15 00:00:00 UTC 2007)
Volume (Year)
121 (2007)
Product Usage
-
Gene expression profiling of human mesenchymal stem cells chemotactically induced with CXCL12.
Authors
Stich S, Haag M, Haupl T, Sezer O, Notter M, Kaps C, Sittinger M, Ringe J
Journal
Cell Tissue Res - Page No 225 (Fri May 01 00:00:00 UTC 2009)
Volume (Year)
336 (2009)
Product Usage
-
Assessment of the U937 cell line for the detection of contact allergens.
Authors
Python F, Goebel C, Aeby P
Journal
Toxicol Appl Pharmacol - Page No 113 (Sun Apr 15 00:00:00 UTC 2007)
Volume (Year)
220 (2007)
Product Usage
-
Th17 cytokines interleukin (IL)-17 and IL-22 modulate distinct inflammatory and keratinocyte-response pathways.
Authors
Nograles KE, Zaba LC, Guttman-Yassky E, Fuentes-Duculan J, Suarez-Farinas M, Cardinale I, Khatcherian A, Gonzalez J, Pierson KC, White TR, Pensabene C, Coats I, Novitskaya I, Lowes MA, Krueger JG
Journal
Br J Dermatol - Page No 1092 (Sat Nov 01 00:00:00 UTC 2008)
Volume (Year)
159 (2008)
Product Usage
-
Epstein-Barr virus-encoded EBNA1 modulates the AP-1 transcription factor pathway in nasopharyngeal carcinoma cells and enhances angiogenesis in vitro.
Authors
O'Neil JD, Owen TJ, Wood VH, Date KL, Valentine R, Chukwuma MB, Arrand JR, Dawson CW, Young LS
Journal
J Gen Virol - Page No 2833 (Sat Nov 01 00:00:00 UTC 2008)
Volume (Year)
89 (2008)
Product Usage
-
Cigarette smoke-induced pulmonary endothelial dysfunction is partially suppressed by sildenafil.
Authors
Milara J, Juan G, Ortiz JL, Guijarro R, Losada M, Serrano A, Morcillo EJ, Cortijo J
Journal
Eur J Pharm Sci - Page No 363 (Thu Mar 18 00:00:00 UTC 2010)
Volume (Year)
39 (2010)
Product Usage
-
Inflammatory and microRNA Gene Expression as Prognostic Classifiers of Barrett's Associated Esophageal Adenocarcinoma.
Authors
Nguyen GH, Schetter AJ, Chou DB, Bowman ED, Zhao R, Hawkes JE, Mathe E, Kumamoto K, Zhao Y, Budhu A, Hagiwara N, Wang XW, Miyashita M, Casson AG, Harris CC
Journal
Clin Cancer Res - Page No (Mon Oct 25 00:00:00 UTC 2010)
Volume (Year)
 (2010)
Product Usage
-
Hyperglycemia and lipopolysaccharide decrease depression effect of interleukin 8 production by hypothermia: an experimental study with endothelial cells.
Authors
Noda A, Kinoshita K, Sakurai A, Matsumoto T, Mugishima H, Tanjoh K
Journal
Intensive Care Med - Page No 109 (Tue Jan 01 00:00:00 UTC 2008)
Volume (Year)
34 (2008)
Product Usage
-
CD34+ cells augment endothelial cell differentiation of CD14+ endothelial progenitor cells in vitro.
Authors
Krenning G, van der Strate BW, Schipper M, van Seijen XJ, Fernandes BC, van Luyn MJ, Harmsen MC
Journal
J Cell Mol Med - Page No 2521 (Sat Aug 01 00:00:00 UTC 2009)
Volume (Year)
13 (2009)
Product Usage
-
TLR3-mediated NF-{kappa}B signaling in human esophageal epithelial cells.
Authors
Lim DM, Narasimhan S, Michaylira CZ, Wang ML
Journal
Am J Physiol Gastrointest Liver Physiol - Page No G1172 (Tue Dec 01 00:00:00 UTC 2009)
Volume (Year)
297 (2009)
Product Usage
-
Expression of angiostatic platelet factor-4var/CXCL4L1 counterbalances angiogenic impulses of vascular endothelial growth factor, interleukin-8/CXCL8, and stromal cell-derived factor 1/CXCL12 in esophageal and colorectal cancer.
Authors
Verbeke H, De Hertogh G, Li S, Vandercappellen J, Noppen S, Schutyser E, El-Asrar AA, Opdenakker G, Van Damme J, Geboes K, Struyf S
Journal
Hum Pathol - Page No 990 (Thu Jul 01 00:00:00 UTC 2010)
Volume (Year)
41 (2010)
Product Usage
-
Gene expression in juvenile arthritis and spondyloarthropathy: pro-angiogenic ELR+ chemokine genes relate to course of arthritis.
Authors
Barnes MG, Aronow BJ, Luyrink LK, Moroldo MB, Pavlidis P, Passo MH, Grom AA, Hirsch R, Giannini EH, Colbert RA, Glass DN, Thompson SD
Journal
Rheumatology (Oxford) - Page No 973 (Sun Aug 01 00:00:00 UTC 2004)
Volume (Year)
43 (2004)
Product Usage
-
The candidate tumor suppressor CST6 alters the gene expression profile of human breast carcinoma cells: down-regulation of the potent mitogenic, motogenic, and angiogenic factor autotaxin.
Authors
Song J, Jie C, Polk P, Shridhar R, Clair T, Zhang J, Yin L, Keppler D
Journal
Biochem Biophys Res Commun - Page No 175 (Fri Feb 03 00:00:00 UTC 2006)
Volume (Year)
340 (2006)
Product Usage
-
HIV-1-infected and/or immune-activated macrophages regulate astrocyte CXCL8 production through IL-1beta and TNF-alpha: involvement of mitogen-activated protein kinases and protein kinase R.
Authors
Zheng JC, Huang Y, Tang K, Cui M, Niemann D, Lopez A, Morgello S, Chen S
Journal
J Neuroimmunol - Page No 100 (Sat Aug 30 00:00:00 UTC 2008)
Volume (Year)
200 (2008)
Product Usage
-
Identification of high and low responders to lipopolysaccharide in normal subjects: an unbiased approach to identify modulators of innate immunity.
Authors
Wurfel MM, Park WY, Radella F, Ruzinski J, Sandstrom A, Strout J, Bumgarner RE, Martin TR
Journal
J Immunol - Page No 2570 (Mon Aug 15 00:00:00 UTC 2005)
Volume (Year)
175 (2005)
Product Usage
-
Leukocytes are primed in peripheral blood for activation during term and preterm labour.
Authors
Yuan M, Jordan F, McInnes IB, Harnett MM, Norman JE
Journal
Mol Hum Reprod - Page No 713 (Sun Nov 01 00:00:00 UTC 2009)
Volume (Year)
15 (2009)
Product Usage
-
Polarized response of endothelial cells to invasion by Aspergillus fumigatus.
Authors
Kamai Y, Lossinsky AS, Liu H, Sheppard DC, Filler SG
Journal
Cell Microbiol - Page No 170 (Thu Jan 01 00:00:00 UTC 2009)
Volume (Year)
11 (2009)
Product Usage
-
cis-Urocanic acid initiates gene transcription in primary human keratinocytes.
Authors
Kaneko K, Smetana-Just U, Matsui M, Young AR, John S, Norval M, Walker SL
Journal
J Immunol - Page No 217 (Tue Jul 01 00:00:00 UTC 2008)
Volume (Year)
181 (2008)
Product Usage
-
Macrophage-secreted factors inhibit ZAG expression and secretion by human adipocytes.
Authors
Gao D, Trayhurn P, Bing C
Journal
Mol Cell Endocrinol - Page No 135 (Mon Aug 30 00:00:00 UTC 2010)
Volume (Year)
325 (2010)
Product Usage
-
Increased interleukin (IL)-1beta messenger ribonucleic acid expression in beta -cells of individuals with type 2 diabetes and regulation of IL-1beta in human islets by glucose and autostimulation.
Authors
Boni-Schnetzler M, Thorne J, Parnaud G, Marselli L, Ehses JA, Kerr-Conte J, Pattou F, Halban PA, Weir GC, Donath MY
Journal
J Clin Endocrinol Metab - Page No 4065 (Wed Oct 01 00:00:00 UTC 2008)
Volume (Year)
93 (2008)
Product Usage
-
Myeloid ELF1-like factor is a potent activator of interleukin-8 expression in hematopoietic cells.
Authors
Hedvat CV, Yao J, Sokolic RA, Nimer SD
Journal
J Biol Chem - Page No 6395 (Fri Feb 20 00:00:00 UTC 2004)
Volume (Year)
279 (2004)
Product Usage
-
Sphingosine-1-phosphate increases human alveolar epithelial IL-8 secretion, proliferation and neutrophil chemotaxis.
Authors
Milara J, Mata M, Mauricio MD, Donet E, Morcillo EJ, Cortijo J
Journal
Eur J Pharmacol - Page No 132 (Fri May 01 00:00:00 UTC 2009)
Volume (Year)
609 (2009)
Product Usage
-
Gram-positive and Gram-negative bacteria synergize with oxidants to release CXCL8 from innate immune cells.
Authors
Paul-Clark MJ, Sorrentino R, Bailey LK, Sriskandan S, Mitchell JA
Journal
Mol Med - Page No 238 (Thu May 01 00:00:00 UTC 2008)
Volume (Year)
14 (2008)
Product Usage
-
Coagulation factor Xa stimulates interleukin-8 release in endothelial cells and mononuclear leukocytes: implications in acute myocardial infarction.
Authors
Busch G, Seitz I, Steppich B, Hess S, Eckl R, Schomig A, Ott I
Journal
Arterioscler Thromb Vasc Biol - Page No 461 (Tue Feb 01 00:00:00 UTC 2005)
Volume (Year)
25 (2005)
Product Usage
-
Angiogenic transcriptome of human microvascular endothelial cells: Effect of hypoxia, modulation by atorvastatin.
Authors
Loboda A, Jazwa A, Jozkowicz A, Molema G, Dulak J
Journal
Vascul Pharmacol - Page No 206 (Sat Apr 01 00:00:00 UTC 2006)
Volume (Year)
44 (2006)
Product Usage
-
Tissue factor and IL8 production by P-selectin-dependent platelet-monocyte aggregates in whole blood involves phosphorylation of Lyn and is inhibited by IL10.
Authors
Christersson C, Johnell M, Siegbahn A
Journal
J Thromb Haemost - Page No 986 (Sun Jun 01 00:00:00 UTC 2008)
Volume (Year)
6 (2008)
Product Usage
-
Differential expression patterns of cytokines in complex regional pain syndrome.
Authors
Uceyler N, Eberle T, Rolke R, Birklein F, Sommer C
Journal
Pain - Page No 195 (Thu Nov 01 00:00:00 UTC 2007)
Volume (Year)
132 (2007)
Product Usage
-
Overexpression of the CXCL3 gene in response to oxidized low-density lipoprotein is associated with the presence of tendon xanthomas in familial hypercholesterolemia.
Authors
Martin-Fuentes P, Civeira F, Solanas-Barca M, Garcia-Otin AL, Jarauta E, Cenarro A
Journal
Biochem Cell Biol - Page No 493 (Mon Jun 01 00:00:00 UTC 2009)
Volume (Year)
87 (2009)
Product Usage
-
Molecular discrimination of responders and nonresponders to anti-TNF alpha therapy in rheumatoid arthritis by etanercept.
Authors
Koczan D, Drynda S, Hecker M, Drynda A, Guthke R, Kekow J, Thiesen HJ
Journal
Arthritis Res Ther - Page No R50 (Tue Jan 01 00:00:00 UTC 2008)
Volume (Year)
10 (2008)
Product Usage
-
The tumor suppressor PRDM5 regulates Wnt signaling at early stages of zebrafish development.
Authors
Meani N, Pezzimenti F, Deflorian G, Mione M, Alcalay M
Journal
Plos One - Page No e4273 (Thu Jan 01 00:00:00 UTC 2009)
Volume (Year)
4 (2009)
Product Usage
-
The synthetic melanocortin (CKPV)2 exerts broad anti-inflammatory effects in human neutrophils.
Authors
Capsoni F, Ongari A, Colombo G, Turcatti F, Catania A
Journal
Peptides - Page No 2016 (Mon Oct 01 00:00:00 UTC 2007)
Volume (Year)
28 (2007)
Product Usage
-
Liver X receptor is a therapeutic target for photoaging and chronological skin aging.
Authors
Chang KC, Shen Q, Oh IG, Jelinsky SA, Jenkins SF, Wang W, Wang Y, LaCava M, Yudt MR, Thompson CC, Freedman LP, Chung JH, Nagpal S
Journal
Mol Endocrinol - Page No 2407 (Sat Nov 01 00:00:00 UTC 2008)
Volume (Year)
22 (2008)
Product Usage
-
Selective regulation of MAP kinases and chemokine expression after ligation of ICAM-1 on human airway epithelial cells.
Authors
Krunkosky TM, Jarrett CL
Journal
Respir Res - Page No 12 (Sun Jan 01 00:00:00 UTC 2006)
Volume (Year)
7 (2006)
Product Usage
-
Differential effects of NF-{kappa}B and p38 MAPK inhibitors and combinations thereof on TNF-{alpha}- and IL-1{beta}-induced proinflammatory status of endothelial cells in vitro.
Authors
Kuldo JM, Westra J, Asgeirsdottir SA, Kok RJ, Oosterhuis K, Rots MG, Schouten JP, Limburg PC, Molema G
Journal
Am J Physiol Cell Physiol - Page No C1229 (Tue Nov 01 00:00:00 UTC 2005)
Volume (Year)
289 (2005)
Product Usage
-
Hepatitis C virus proteins interfere with the activation of chemokine gene promoters and downregulate chemokine gene expression.
Authors
Sillanpaa M, Kaukinen P, Melen K, Julkunen I
Journal
J Gen Virol - Page No 432 (Fri Feb 01 00:00:00 UTC 2008)
Volume (Year)
89 (2008)
Product Usage
-
Inflammation anergy in human intestinal macrophages is due to Smad-induced IkappaBalpha expression and NF-kappaB inactivation.
Authors
Smythies LE, Shen R, Bimczok D, Novak L, Clements RH, Eckhoff DE, Bouchard P, George MD, Hu WK, Dandekar S, Smith PD
Journal
J Biol Chem - Page No 19593 (Fri Jun 18 00:00:00 UTC 2010)
Volume (Year)
285 (2010)
Product Usage
-
Skin sensitization to p-phenylenediamine: the diverging roles of oxidation and N-acetylation for dendritic cell activation and the immune response.
Authors
Aeby P, Sieber T, Beck H, Gerberick GF, Goebel C
Journal
J Invest Dermatol - Page No 99 (Thu Jan 01 00:00:00 UTC 2009)
Volume (Year)
129 (2009)
Product Usage
-
Postmenopausal expression changes of immune system-related genes in human bone tissue.
Authors
Kosa JP, Balla B, Kiss J, Podani J, Takacs I, Lazary A, Nagy Z, Bacsi K, Karsai A, Speer G, Lakatos P
Journal
J Clin Immunol - Page No 761 (Sun Nov 01 00:00:00 UTC 2009)
Volume (Year)
29 (2009)
Product Usage
-
Dissecting the impact of chemotherapy on the human hair follicle: a pragmatic in vitro assay for studying the pathogenesis and potential management of hair follicle dystrophy.
Authors
Bodo E, Tobin DJ, Kamenisch Y, Biro T, Berneburg M, Funk W, Paus R
Journal
Am J Pathol - Page No 1153 (Mon Oct 01 00:00:00 UTC 2007)
Volume (Year)
171 (2007)
Product Usage
-
Characterization of the innate immune signalling pathways in hepatocyte cell lines.
Authors
Preiss S, Thompson A, Chen X, Rodgers S, Markovska V, Desmond P, Visvanathan K, Li K, Locarnini S, Revill P
Journal
J Viral Hepat - Page No 888 (Mon Dec 01 00:00:00 UTC 2008)
Volume (Year)
15 (2008)
Product Usage
-
Calcium pantothenate modulates gene expression in proliferating human dermal fibroblasts.
Authors
Wiederholt T, Heise R, Skazik C, Marquardt Y, Joussen S, Erdmann K, Schroder H, Merk HF, Baron JM
Journal
Exp Dermatol - Page No 969 (Sun Nov 01 00:00:00 UTC 2009)
Volume (Year)
18 (2009)
Product Usage
-
Microarray analysis of gene expression in peripheral blood mononuclear cells from dioxin-exposed human subjects.
Authors
McHale CM, Zhang L, Hubbard AE, Zhao X, Baccarelli A, Pesatori AC, Smith MT, Landi MT
Journal
Toxicology - Page No 101 (Fri Jan 05 00:00:00 UTC 2007)
Volume (Year)
229 (2007)
Product Usage
-
Enhanced expression of interleukin-6, matrix metalloproteinase-13, and receptor activator of NF-kappaB ligand in cells derived from osteoarthritic subchondral bone.
Authors
Sakao K, Takahashi KA, Mazda O, Arai Y, Tonomura H, Inoue A, Saito M, Fujioka M, Takamiya H, Imanishi J, Kubo T
Journal
J Orthop Sci - Page No 202 (Thu May 01 00:00:00 UTC 2008)
Volume (Year)
13 (2008)
Product Usage
-
Gene expression analysis of immunostained endothelial cells isolated from formaldehyde-fixated paraffin embedded tumors using laser capture microdissection--a technical report.
Authors
Kaneko T, Okiji T, Kaneko R, Suda H, Nor JE
Journal
Microsc Res Tech - Page No 908 (Tue Dec 01 00:00:00 UTC 2009)
Volume (Year)
72 (2009)
Product Usage
-
Soluble MD-2 is an acute-phase protein and an opsonin for Gram-negative bacteria.
Authors
Tissieres P, Dunn-Siegrist I, Schappi M, Elson G, Comte R, Nobre V, Pugin J
Journal
Blood - Page No 2122 (Fri Feb 15 00:00:00 UTC 2008)
Volume (Year)
111 (2008)
Product Usage
-
Microarray analysis of transcriptional responses to infection by herpes simplex virus types 1 and 2 and their US3-deficient mutants.
Authors
Kamakura M, Nawa A, Ushijima Y, Goshima F, Kawaguchi Y, Kikkawa F, Nishiyama Y
Journal
Microbes Infect - Page No 405 (Tue Apr 01 00:00:00 UTC 2008)
Volume (Year)
10 (2008)
Product Usage
-
Effect of atorvastatin on PM10-induced cytokine production by human alveolar macrophages and bronchial epithelial cells.
Authors
Sakamoto N, Hayashi S, Mukae H, Vincent R, Hogg JC, van Eeden SF
Journal
Int J Toxicol - Page No 17 (Thu Jan 01 00:00:00 UTC 2009)
Volume (Year)
28 (2009)
Product Usage
-
IL-17 secreted by tumor reactive T cells induces IL-8 release by human renal cancer cells.
Authors
Inozume T, Hanada K, Wang QJ, Yang JC
Journal
J Immunother - Page No 109 (Sun Feb 01 00:00:00 UTC 2009)
Volume (Year)
32 (2009)
Product Usage
-
Gene expression profile of adult human bone marrow-derived mesenchymal stem cells stimulated by the chemokine CXCL7.
Authors
Kalwitz G, Endres M, Neumann K, Skriner K, Ringe J, Sezer O, Sittinger M, Haupl T, Kaps C
Journal
Int J Biochem Cell Biol - Page No 649 (Sun Mar 01 00:00:00 UTC 2009)
Volume (Year)
41 (2009)
Product Usage
-
Gene expression studies in cultured dendritic cells: new indicators for the discrimination of skin sensitizers and irritants in vitro.
Authors
Szameit S, Vierlinger K, Farmer L, Tuschl H, Noehammer C
Journal
Clin Exp Allergy - Page No 856 (Mon Jun 01 00:00:00 UTC 2009)
Volume (Year)
39 (2009)
Product Usage
-
The nucleotide-binding oligomerization domain-like receptor NLRC5 is involved in IFN-dependent antiviral immune responses.
Authors
Kuenzel S, Till A, Winkler M, Hasler R, Lipinski S, Jung S, Grotzinger J, Fickenscher H, Schreiber S, Rosenstiel P
Journal
J Immunol - Page No 1990 (Mon Feb 15 00:00:00 UTC 2010)
Volume (Year)
184 (2010)
Product Usage
-
Osteoblasts derived from osteophytes produce interleukin-6, interleukin-8, and matrix metalloproteinase-13 in osteoarthritis.
Authors
Sakao K, Takahashi KA, Arai Y, Saito M, Honjo K, Hiraoka N, Asada H, Shin-Ya M, Imanishi J, Mazda O, Kubo T
Journal
J Bone Miner Metab - Page No 412 (Thu Jan 01 00:00:00 UTC 2009)
Volume (Year)
27 (2009)
Product Usage
-
Effects of p38 mitogen-activated protein kinase inhibition on anti-neutrophil cytoplasmic autoantibody pathogenicity in vitro and in vivo.
Authors
van der Veen BS, Chen M, Muller R, van Timmeren MM, Petersen AH, Lee PA, Satchell SC, Mathieson PW, Saleem MA, Stegeman CA, Zwerina J, Molema G, Heeringa P
Journal
Ann Rheum Dis - Page No (Tue Nov 09 00:00:00 UTC 2010)
Volume (Year)
 (2010)
Product Usage
-
Gene expression by human monocytes from peripheral blood in response to exposure to metals.
Authors
Jost-Albrecht K, Hofstetter W
Journal
J Biomed Mater Res B Appl Biomater - Page No 449 (Wed Feb 01 00:00:00 UTC 2006)
Volume (Year)
76 (2006)
Product Usage
-
Autocrine inhibitory influences of alpha-melanocyte-stimulating hormone in malignant pleural mesothelioma.
Authors
Catania A, Colombo G, Carlin A, Garofalo L, Gatti S, Buffa R, Carboni N, Rosso L, Santambrogio L, Cantalamessa L, Lipton JM
Journal
J Leukoc Biol - Page No 253 (Sun Feb 01 00:00:00 UTC 2004)
Volume (Year)
75 (2004)
Product Usage
-
Functional inhibition of NF-kappaB signal transduction in alphavbeta3 integrin expressing endothelial cells by using RGD-PEG-modified adenovirus with a mutant IkappaB gene.
Authors
Ogawara K, Kuldo JM, Oosterhuis K, Kroesen BJ, Rots MG, Trautwein C, Kimura T, Haisma HJ, Molema G
Journal
Arthritis Res Ther - Page No R32 (Sun Jan 01 00:00:00 UTC 2006)
Volume (Year)
8 (2006)
Product Usage
-
Reactive oxygen species (ROS) reduce the expression of BRAK/CXCL14 in human head and neck squamous cell carcinoma cells.
Authors
Maehata Y, Ozawa S, Kobayashi K, Kato Y, Yoshino F, Miyamoto C, Izukuri K, Kubota E, Hata R, Lee MC
Journal
Free Radic Res - Page No 913 (Sun Aug 01 00:00:00 UTC 2010)
Volume (Year)
44 (2010)
Product Usage
-
Interleukin-32gamma enhances the production of IL-6 and IL-8 in fibroblast-like synoviocytes via Erk1/2 activation.
Authors
Kim YG, Lee CK, Kim SH, Cho WS, Mun SH, Yoo B
Journal
J Clin Immunol - Page No 260 (Mon Mar 01 00:00:00 UTC 2010)
Volume (Year)
30 (2010)
Product Usage
-
Modulation of host gene expression by the K15 protein of Kaposi's sarcoma-associated herpesvirus.
Authors
Brinkmann MM, Pietrek M, Dittrich-Breiholz O, Kracht M, Schulz TF
Journal
J Virol - Page No 42 (Mon Jan 01 00:00:00 UTC 2007)
Volume (Year)
81 (2007)
Product Usage
-
Combined inhibition of complement and CD14 abolish E. coli-induced cytokine-, chemokine- and growth factor-synthesis in human whole blood.
Authors
Brekke OL, Christiansen D, Fure H, Pharo A, Fung M, Riesenfeld J, Mollnes TE
Journal
Mol Immunol - Page No 3804 (Fri Aug 01 00:00:00 UTC 2008)
Volume (Year)
45 (2008)
Product Usage
-
Differential expression of immunoregulatory genes in monocytes in response to Porphyromonas gingivalis and Escherichia coli lipopolysaccharide.
Authors
Barksby HE, Nile CJ, Jaedicke KM, Taylor JJ, Preshaw PM
Journal
Clin Exp Immunol - Page No 479 (Mon Jun 01 00:00:00 UTC 2009)
Volume (Year)
156 (2009)
Product Usage
-
Temporal-spatial analysis of U.S.-Mexico border environmental fine and coarse PM air sample extract activity in human bronchial epithelial cells.
Authors
Lauer FT, Mitchell LA, Bedrick E, McDonald JD, Lee WY, Li WW, Olvera H, Amaya MA, Berwick M, Gonzales M, Currey R, Pingitore NE Jr, Burchiel SW
Journal
Toxicol Appl Pharmacol - Page No 1 (Wed Jul 01 00:00:00 UTC 2009)
Volume (Year)
238 (2009)
Product Usage
-
Gene expression signals involved in ischemic injury, extracellular matrix composition and fibrosis defined by global mRNA profiling of the human left ventricular myocardium.
Authors
Gabrielsen A, Lawler PR, Yongzhong W, Steinbruchel D, Blagoja D, Paulsson-Berne G, Kastrup J, Hansson GK
Journal
J Mol Cell Cardiol - Page No 870 (Sun Apr 01 00:00:00 UTC 2007)
Volume (Year)
42 (2007)
Product Usage
-
Local and systemic cytokine and chemokine responses after parenteral influenza vaccination.
Authors
Eriksson JC, Cox RJ, Szyszko E, Davidsson A, Brokstad KA
Journal
Influenza Other Respi Viruses - Page No 139 (Sun Jul 01 00:00:00 UTC 2007)
Volume (Year)
1 (2007)
Product Usage
-
Social regulation of gene expression in human leukocytes.
Authors
Cole SW, Hawkley LC, Arevalo JM, Sung CY, Rose RM, Cacioppo JT
Journal
Genome Biol - Page No R189 (Mon Jan 01 00:00:00 UTC 2007)
Volume (Year)
8 (2007)
Product Usage
-
Transcriptional program induced by factor VIIa-tissue factor, PAR1 and PAR2 in MDA-MB-231 cells.
Authors
Albrektsen T, Sorensen BB, Hjorto GM, Fleckner J, Rao LV, Petersen LC
Journal
J Thromb Haemost - Page No 1588 (Wed Aug 01 00:00:00 UTC 2007)
Volume (Year)
5 (2007)
Product Usage
-

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