WRCH1 Proteins

Protein Information

This gene encodes a member of the Rho family of GTPases. This protein can activate PAK1 and JNK1, and can induce filopodium formation and stress fiber dissolution. It may also mediate the effects of WNT1 signaling in the regulation of cell morphology, cytoskeletal organization, and cell proliferation. A non-coding transcript variant of this gene results from naturally occurring read-through transcription between this locus and the neighboring DUSP5P (dual specificity phosphatase 5 pseudogene) locus.

Synonyms

2310026M05Rik; AI182090; Arhu; CDC42L1; CDC42-like GTPase 1; G28K; GTP-binding protein like 1; GTP-binding protein SB128; GTP-binding protein-like 1; hG28K; LOC678766; mG28K; ras homolog family member U; ras homolog gene family, member U; ras-like gene family member U; Ras-like protein member U; Rho GTPase-like protein ARHU; rho-related GTP-binding protein RhoU; RHOU; Ryu GTPase; SB128; similar to ras homolog gene family, member U; Wnt1 responsive Cdc42 homolog; wnt-1 responsive Cdc42 homolog 1; WRCH1; WRCH-1