TIMM8B Proteins

Protein Information

This gene encodes a member of a well-conserved family of proteins with similarity to yeast Tim mitochondrial import proteins. This gene is encoded by a nuclear gene and is transported into the intermembrane space of the mitochondrion. When formed into complexes, these proteins guide membrane-spanning proteins across the mitochondrial intermembrane space before they are added into the mitochondrial inner membrane. This gene is adjacent to succinate dehydrogenase, subunit D (SDHD), in which mutations have been found in affected members of families with hereditary paraganglioma.

Synonyms

Ddp2; DDPL; DDP-like protein; Deafness dystonia protein 2; deafness dystonia protein 2 homolog; Mitochondrial import inner membrane translocase subunit Tim8 B; small zinc finger-like protein DDP2; Tim8b; TIMM8B; translocase of inner mitochondrial membrane 8 homolog B; translocase of inner mitochondrial membrane 8 homolog b (yeast); translocase of inner mitochondrial membrane 8B