TIMM50 Proteins

Protein Information

TIMM50 (Mitochondrial import inner membrane translocase subunit TIM50) is an enzyme that in humans is encoded by the TIMM50 gene. Tim50 is a subunit of the Tim23 translocase complex in the inner mitochondrial membrane. Mutations in TIMM50 can lead to epilepsy, severe intellectual disability, and 3-methylglutaconic aciduria. TIMM50 expression is increased in breast cancer cells and decreased in hypertrophic hearts.

Synonyms

2810403L02Rik; AU015082; homolog of yeast Tim50; LOC687295; MGC102733; mitochondrial import inner membrane translocase subunit TIM50; PRO1512; similar to translocase of inner mitochondrial membrane 50 homolog; TIM50; TIM50L; Tim50-like protein; Timm50; translocase of inner mitochondrial membrane 50; translocase of inner mitochondrial membrane 50 homolog