TCEA3 Proteins

Protein Information

Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus.

Synonyms

rhabdomyosarcoma antigen MU-RMS-40.22; S-II; SII-K1; TCEA3; TFIIS; TFIIS.H; Tfiish; tissue-specific transcription factor S-II; transcription elongation factor A (SII), 3; transcription elongation factor A protein 3; transcription elongation factor A3; transcription elongation factor S-II protein 3; Transcription elongation factor TFIIS.h