TALDO1 Proteins

Protein Information

Transaldolase 1 is a key enzyme of the nonoxidative pentose phosphate pathway providing ribose-5-phosphate for nucleic acid synthesis and NADPH for lipid biosynthesis. This pathway can also maintain glutathione at a reduced state and thus protect sulfhydryl groups and cellular integrity from oxygen radicals. The functional gene of transaldolase 1 is located on chromosome 11 and a pseudogene is identified on chromosome 1 but there are conflicting map locations. The second and third exon of this gene were developed by insertion of a retrotransposable element. This gene is thought to be involved in multiple sclerosis.

Synonyms

dihydroxyacetone transferase; glycerone transferase; TAL; Taldo; TALDO1; TALDOR; TALH; TAL-H; testicular secretory protein Li 56; transaldolase; transaldolase 1