PSD Proteins

Protein Information

PSD, which called EFA6A, is 63% identical to EFA6B (PSD4) and contains a Sec7 domain adjacent to a PH domain, followed by a C-terminal coiled-coil motif. This gene is mapped to chromosome 10q24. And it encodes a Plekstrin homology and SEC7 domains-containing protein that functions as a guanine nucleotide exchange factor. The encoded protein regulates signal transduction by activating ADP-ribosylation factor 6. Alternative splicing results in multiple transcript variants.

Synonyms

1110007H17Rik; A930015K15; EFA6; EFA6A; Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6; Exchange factor for ARF6; Exchange factor for ARF6 A; Kiaa2011; mKIAA2011; PH and SEC7 domain-containing protein 1; pleckstrin and Sec7 domain containing; pleckstrin and Sec7 domain containing homolog; pleckstrin homology and SEC7 domain-containing protein 1; pleckstrin-Sec7 domains-containing; Psd; Psd1; Psdl; TYL