PRRG1 Proteins

Protein Information

This gene encodes a vitamin K-dependent, gamma-carboxyglutamic acid (Gla)-containing, single-pass transmembrane protein. This protein contains a Gla domain at the N-terminus, preceded by a propeptide sequence required for post-translational gamma-carboxylation of specific glutamic acid residues by a vitamin K-dependent gamma-carboxylase. The C-terminus is proline-rich containing PPXY and PXXP motifs found in a variety of signaling and cytoskeletal proteins. This gene is highly expressed in the spinal cord. Several alternatively spliced transcript variants have been found for this gene.

Synonyms

2010007L08Rik; ortholog of proline rich Gla (G-carboxyglutamic acid) 1 PRRG1; PRGP1; proline rich and Gla domain 1; proline rich Gla (G-carboxyglutamic acid) 1; Proline-rich gamma-carboxyglutamic acid protein 1; proline-rich Gla (G-carboxyglutamic acid) polypeptide 1; Proline-rich Gla protein 1; PRRG1; RGD1561320; TMG1; Transmembrane gamma-carboxyglutamic acid protein 1