PRMT7 Proteins

Protein Information

Arginine methylation is an irreversible post translational modification which has been implicated in RNA processing and trafficking, receptor-mediated signaling, and transcription. At least three types of PRMT enzymes have been identified in mammalian cells. These enzymes have been shown to have essential regulatory functions by methylation of key proteins in several fundamental areas. These proteins include nuclear proteins, IL enhancer binding factor, nuclear factors, cell cycle proteins, signal transduction proteins, apoptosis proteins, and viral proteins. The mammalian PRMT family currently consists of 7 members that share two large domains of homology. Outside of these domains, epitopes were identified and antibodies against all 7 PRMT members have been developed.

Synonyms

[Myelin basic protein]-arginine N-methyltransferase PRMT7; 4933402B05Rik; BC006705; FLJ10640; Histone-arginine N-methyltransferase PRMT7; Kiaa1933; myelin basic protein-arginine N-methyltransferase; Prmt7; PRMT-7; protein arginine methyltransferase 7; protein arginine N-methyltransferase 7; RGD1304869