PEO1 Proteins

Protein Information

Twinkle is a mitochondrial protein with structural similarity to the phage T7 primase/helicase (GP4) and other hexameric ring helicases. The twinkle protein colocalizes with mtDNA in mitochondrial nucleoids, and its name derives from the unusual localization pattern reminiscent of twinkling stars.Twinkle is a mitochondrial protein with structural similarity to the phage T7 primase/helicase (GP4) and other hexameric ring helicases. The twinkle protein colocalizes with mtDNA in mitochondrial nucleoids, and its name derives from the unusual localization pattern reminiscent of twinkling stars (Spelbrink et al., 2001 [PubMed 11431692]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Synonyms

ataxin 8; Ataxin8; ATXN 8; ATXN8; C10 orf2; C10orf 2; C10orf2; chromosome 10 open reading frame 2; D19Ertd626e; FLJ21832; IOSCA; mitochondrial twinkle protein; MTDPS7; PEO; PEO 1; Peo1; PEOA3; PRLTS5; progressive external ophthalmoplegia 1; progressive external ophthalmoplegia 1 (human); progressive external ophthalmoplegia 1 homolog; progressive external ophthalmoplegia 1 protein; Progressive external ophthalmoplegia 1 protein homolog; SANDO; SCA 8; SCA8; T7 gp4-like protein with intramitochondrial nucleoid localization; T7 helicase-related protein with intramitochondrial nucleoid localization; T7-like mitochondrial DNA helicase; Twinkle mtDNA helicase; Twinkle protein, mitochondrial; TWINL; TWNK