PDE12 Proteins

PDE12 Human recombinant proteins are validated for use in the following applications: Blocking Assay. Available Product Grades: RUO. Browse 1 protein. Not finding the exact protein, grade or size needed?... PDE12 Human recombinant proteins are validated for use in the following applications: Blocking Assay. Available Product Grades: RUO. Browse 1 protein. Not finding the exact protein, grade or size needed? Contact us to discuss your specific application and product needs.... PDE12 Human recombinant proteins are validated for use in the following applications: Blocking Assay. Available Product Grades: RUO. Browse 1 protein. Not finding the exact protein, grade or size needed? Contact us to discuss your specific application and product needs.... PDE12 Human recombinant proteins are validated for use in the following applications: Blocking Assay. Available Product Grades: RUO. Browse 1 protein. Not finding the exact protein, grade or size needed? Contact us to discuss your specific application and product needs.

Protein Information

PDE12 is an enzyme that cleaves 2',5'-phosphodiester bond linking adenosines of the 5'-triphosphorylated oligoadenylates, triphosphorylated oligoadenylates referred as 2-5A modulates the 2-5A system. This enzyme degraded triphosphorylated 2-5A to produce AMP and ATP. It also cleaves 3',5'-phosphodiester bond of oligoadenylates and plays a role as a negative regulator of the 2-5A system that is one of the major pathways for antiviral and antitumor functions induced by interferons (IFNs). Suppression of this enzyme induces reduction of viral replication in Hela cells, thus counteracting the antiviral pathway probably by inhibiting the 2-5A system.

Synonyms

2',5'-phosphodiesterase 12; 2'-PDE; 2-PDE; 2'-phosphodiesterase; E430028B21Rik; LRRGT00074; Mitochondrial deadenylase; PDE12; phosphodiesterase 12; RGD1310975

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Invitrogen

Human PDE12 (aa 494-586) Control Fragment Recombinant Protein

Invitrogen

Human PDE12 (aa 494-586) Control Fragment Recombinant Protein

Species

Human

Expression System

E. coli

Product Grade

Research Use Only

Application

Ctrl BLOCK

Price

Cat # RP-100240

100 µL

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PDE12 Proteins

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