MARCO Proteins

MARCO Human recombinant proteins are validated for use in the following applications: Blocking Assay. Available Product Grades: RUO. Browse 1 protein. Not finding the exact protein, grade or size needed?... MARCO Human recombinant proteins are validated for use in the following applications: Blocking Assay. Available Product Grades: RUO. Browse 1 protein. Not finding the exact protein, grade or size needed? Contact us to discuss your specific application and product needs.... MARCO Human recombinant proteins are validated for use in the following applications: Blocking Assay. Available Product Grades: RUO. Browse 1 protein. Not finding the exact protein, grade or size needed? Contact us to discuss your specific application and product needs.... MARCO Human recombinant proteins are validated for use in the following applications: Blocking Assay. Available Product Grades: RUO. Browse 1 protein. Not finding the exact protein, grade or size needed? Contact us to discuss your specific application and product needs.

Protein Information

MARCO, also known as SR-A6 or SCARA2, is a macrophage surface receptor and a member of the class A scavenger receptor family. As a part of the innate antimicrobial immune system, MARCO can bind both Gram-negative and Gram-positive bacteria via an extracellular, C-terminal, scavenger receptor cysteine-rich (SRCR) domain. In addition to short cytoplasmic and transmembrane domains, there is an extracellular spacer domain and a long, extracellular collagenous domain. The protein may form a trimeric molecule by the association of the collagenous domains of three identical polypeptide chains. Due to its expression in tumor infiltrating macrophages, and its role in inhibiting immune responses within tumor environment, MARCO has been indicated as a potential target for cancer immunotherapy.

Synonyms

AI323439; Ly112; Macrophage receptor MARCO; macrophage receptor with collagenous structure; Marco; SCARA2; Scavenger receptor class A member 2; scavenger receptor class A, member 2; SR-A6

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Invitrogen

Human MARCO (aa 68-125) Control Fragment Recombinant Protein

Invitrogen

Human MARCO (aa 68-125) Control Fragment Recombinant Protein

Species

Human

Expression System

E. coli

Product Grade

Research Use Only

Application

Ctrl BLOCK

Price

Cat # RP-103527

100 µL

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MARCO Proteins

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