DPM1 Proteins

Protein Information

Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Lack of Dol-P-Man results in defective surface expression of GPI-anchored proteins. Dol-P-Man is synthesized from GDP-mannose and dolichol-phosphate on the cytosolic side of the ER by the enzyme dolichyl-phosphate mannosyltransferase. Human DPM1 lacks a carboxy-terminal transmembrane domain and signal sequence and is regulated by DPM2.

Synonyms

AI118379; AI194292; CDGIE; dolichol monophosphate mannose synthase; dolichol-phosphate (beta-D) mannosyltransferase 1; Dolichol-phosphate mannose synthase; dolichol-phosphate mannose synthase subunit 1; Dolichol-phosphate mannosyltransferase; Dolichol-phosphate mannosyltransferase subunit 1; dolichyl-phosphate beta-D-mannosyltransferase; Dolichyl-phosphate beta-D-mannosyltransferase subunit 1; dolichyl-phosphate mannosyltransferase 1; dolichyl-phosphate mannosyltransferase polypeptide 1 catalytic subunit; dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit; DPM synthase; DPM synthase complex, catalytic subunit; DPM synthase subunit 1; Dpm1; Mannose-P-dolichol synthase; Mannose-P-dolichol synthase subunit 1; MPD synthase; MPD synthase subunit 1; MPDS; OTTMUSP00000017164; P9705.3; RP23-391M18.1; SED3; YPR183W