DPH2 Proteins

Protein Information

This gene is one of two human genes similar to the yeast gene dph2. The yeast gene was identified by its ability to complement a diphthamide mutant strain, and thus probably functions in diphthamide biosynthesis. Diphthamide is a post-translationally modified histidine residue present in elongation factor 2 (EF2) that is the target of diphtheria toxin ADP-ribosylation. Two transcript variants encoding different isoforms have been found for this gene.

Synonyms

2-(3-amino-3-carboxypropyl)histidine synthase subunit 2; 9130020C19Rik; AI467389; Diphthamide biosynthesis protein 2; diphthamide biosynthesis protein 2 homolog-like 2; diphthamide biosynthesis-like protein 2; Diphtheria toxin resistance protein 2; diptheria toxin resistance protein required for diphthamide biosynthesis (Saccharomyces)-like 1; diptheria toxin resistance protein required for diphthamide biosynthesis (Saccharomyces)-like 2; diptheria toxin resistance protein required for diphthamide biosynthesis-like 2; DPH2; DPH2 homolog; DPH2 homolog (S. cerevisiae); Dph2l2; DPH2-like 2; MmDph2; S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 2; S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase DPH2