DLX5 Proteins

Protein Information

This gene encodes a member of a homeobox transcription factor gene family similar to the Drosophila distal-less gene. The encoded protein may play a role in bone development and fracture healing. Mutation in this gene, which is located in a tail-to-tail configuration with another member of the family on the long arm of chromosome 7, may be associated with split-hand/split-foot malformation.

Synonyms

AI385752; distal-less homeo box 5; distal-less homeobox 5; DLX-3; DLX5; Homeobox protein DLX-3; homeobox protein DLX-5; RDLX; SHFM1D; split hand/foot malformation type 1 with sensorineural hearing loss