DLK1 Proteins

Protein Information

The Delta-like 1 homolog (DLK1) is a transmembrane protein containing six epidermal growth factor repeats. It is involved in the differentiation of several cell types, including adipocytes and is also thought to be a tumor suppressor. The DLK1 gene is one of several imprinted genes located in a region on chromosome 14q32; certain mutations in this imprinted region can cause phenotypes similar to maternal and paternal uniparental disomy of chromosome 14 (UPD14). DLK1 is expressed from the paternal allele; a polymorphism within this gene has been associated with child and adolescent obesity.

Synonyms

Adipocyte differentiation inhibitor protein; AW742678; delta like non-canonical Notch ligand 1; Delta1; delta-like 1 homolog; delta-like 1 homolog (Drosophila); DLK; DLK1; DLK-1; DlkI; FA1; Fetal antigen 1; Ly107; Peg9; pG2; Preadipocyte factor 1; preadipocyte factor-1; PREF; PREF1; Pref-1; Protein delta homolog 1; SCP1; Scp-1; secredeltin; stromal cell derived protein 1; Zog