DDX11 Proteins

Protein Information

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. DDX11 encodes a DEAD box protein, which is an enzyme that possesses both ATPase and DNA helicase activities. DDX11 is a homolog of the yeast CHL1 gene, and may function to maintain chromosome transmission fidelity and genomestability.

Synonyms

4732462I11Rik; ATP-dependent DNA helicase DDX11; CHL1; CHL1-like helicase homolog; CHL1-related helicase gene-1; CHL1-related protein 1; CHLR1; DDX11; DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae); DEAD/H box protein 11; DEAD/H-box helicase 11; DEAD/H-box protein 11; essa15a; hCHLR1; keratinocyte growth factor-regulated gene 2 protein; KRG2; KRG-2; probable ATP-dependent DNA helicase DDX11; probable ATP-dependent RNA helicase DDX11; WABS