DDRGK1 Proteins

Protein Information

Protein which interacts with the E3 UFM1-protein ligase UFL1 and one of its substrates TRIP4 and is required for TRIP4 ufmylation. Through TRIP4 ufmylation may regulate nuclear receptors-mediated transcription. May play a role in NF-kappa-B-mediated transcription through regulation of the phosphorylation and the degradation of NFKBIA, the inhibitor of NF-kappa-B. May also play a role in the cellular response to endoplasmic reticulum stress.

Synonyms

1110001I20Rik; 2600009E05Rik; AI326138; C20orf116; Dashurin; DDRGK domain containing 1; DDRGK domain-containing protein 1; Ddrgk1; dJ1187M17.3; RGD1309979; Ufbp1; UFM1-binding and PCI domain-containing protein 1; UFM1-binding protein 1 containing a PCI domain