DACH2 Proteins

Protein Information

This gene is one of two genes which encode a protein similar to the Drosophila protein dachshund, a transcription factor involved in cell fate determination in the eye, limb and genital disc of the fly. The encoded protein contains two characteristic dachshund domains: an N-terminal domain responsible for DNA binding and a C-terminal domain responsible for protein-protein interactions. This gene is located on the X chromosome and is subject to inactivation by DNA methylation. The encoded protein may be involved in regulation of organogenesis and myogenesis, and may play a role in premature ovarian failure. Multiple transcript variants encoding different isoforms have been found for this gene.

Synonyms

9430028N04Rik; Dach2; dachshund 2; dachshund 2 (Drosophila); dachshund family transcription factor 2; dachshund homolog 2; FLJ31391; MGC138545; RGD1561687; RP11-345E19.1