CYB5R3 Proteins

Protein Information

CYB5R3 (NADH-cytochrome b5, reductase 3, diaphorase 1) is a 301 amino acid protein encoded by the human gene CYB5R3. CYB5R3 belongs to the flavoprotein pyridine nucleotide cytochrome reductase family and has two naturally occuring isoforms. Isoform 1 is anchored to the cytoplasmic side of the endoplasmic reticulum membrane and mitochondrion outer membrane, while isoform 2 is the soluble form found in erythrocytes. CYB5R3 is involved in the desaturation and elongation of fatty acids, cholesterol biosynthesis,drug metabolism and, in erythrocytes, methemoglobin reduction.

Synonyms

0610016L08Rik; 2500002N19Rik; B5R; C5BR; C85115; CB5R; Cyb5r3; cytochrome b5 reductase 3; Dia1; Dia-1; Diaphorase (NADH) (cytochrome b-5 reductase); diaphorase 1; diaphorase 1 (NADH); Diaphorase1; diaphorase-1; LOC100524254; LOW QUALITY PROTEIN: NADH-cytochrome b5 reductase 3-like; mutant NADH-cytochrome b5 reductase; Nadhcb5; NADH-cytochrome b5 reductase 3; NADH-cytochrome b5 reductase 3 membrane-bound form; NADH-cytochrome b5 reductase 3 soluble form; NADH-cytochrome b5 reductase 3-like; RNNADHCB5; WU:AL591952.1-001; WU:AL591952.1-002; WU:AL591952.1-003; WU:Cyb5r3