CtBP2 Proteins

Protein Information

This gene produces alternative transcripts encoding two distinct proteins. One protein is a transcriptional repressor, while the other isoform is a major component of specialized synapses known as synaptic ribbons. Both proteins contain a NAD+ binding domain similar to NAD+-dependent 2-hydroxyacid dehydrogenases. A portion of the 3' untranslated region was used to map this gene to chromosome 21q21. 3; however, it was noted that similar loci elsewhere in the genome are likely. Blast analysis shows that this gene is present on chromosome 10.

Synonyms

AA407280; CtBP2; C-terminal binding protein 2; C-terminal-binding protein 2; D7Ertd45e; gene trap ROSA b-geo 6; Gtrgeo6; Ribeye; RP11-59C5.2