CDY2B Proteins

Protein Information

CDY2B encodes a protein containing a chromodomain and a histone acetyltransferase catalytic domain. Chromodomain proteins are components of heterochromatin-like complexes and can act as gene repressors. This protein is localized to the nucleus of late spermatids where histone hyperacetylation takes place. Histone hyperacetylation is thought to facilitate the transition in which protamines replace histones as the major DNA-packaging protein. Two nearly identical copies of this gene are found in a palindromic region on chromosome Y; this record represents the centromeric copy. Chromosome Y also contains a pair of closely related genes in another more telomeric palindrome as well as several related pseudogenes.

Synonyms

CDY; CDY2; CDY2A; CDY2B; chromodomain protein, Y chromosome, 2 related; chromodomain protein, Y-linked, 2B; testis-specific chromodomain protein Y 2; testis-specific chromodomain protein Y protein 2 related; Y chromosome chromodomain protein 2B