CDK12 Proteins

CDK12 Human recombinant proteins are validated for use in the following applications: Blocking Assay. These proteins are expressed in E. coli. Available Product Grades: RUO. Browse all 2 proteins. Not finding the exact protein, grade or size needed?... CDK12 Human recombinant proteins are validated for use in the following applications: Blocking Assay. These proteins are expressed in E. coli. Available Product Grades: RUO. Browse all 2 proteins. Not finding the exact protein, grade or size needed? Contact us... CDK12 Human recombinant proteins are validated for use in the following applications: Blocking Assay. These proteins are expressed in E. coli. Available Product Grades: RUO. Browse all 2 proteins. Not finding the exact protein, grade or size needed? Contact us to discuss your specific application and product needs.... CDK12 Human recombinant proteins are validated for use in the following applications: Blocking Assay. These proteins are expressed in E. coli. Available Product Grades: RUO. Browse all 2 proteins. Not finding the exact protein, grade or size needed? Contact us to discuss your specific application and product needs.

Protein Information

Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'), a sequence present in many viral and cellular promoters. Activator of the NF-ELAM1/delta-A site of the E-selectin promoter. Has no intrinsic transcriptional activity, but activates transcription on formation of JUN or FOS heterodimers. Also can bind TRE promoter sequences when heterodimerized with members of the JUN family. Isoform 4/ATF-A0acts as a dominant repressor of the E-selectin/NF-ELAM1/delta-A promoter. Isoform 5/ATF-4acts as a negative regulator, inhibiting both ATF2 and ATF7 transcriptional activities. It may exert these effects by sequestrating in the cytoplasm the Thr-53 phosphorylating kinase, preventing activation.

Synonyms

1810022J16Rik; AI646528; CDC2-related kinase 7; CDC2-related kinase, arginine/serine-rich; CDC2-related protein kinase 7; Cdk12; Cell division cycle 2-related protein kinase 7; cell division protein kinase 12; CRK7; CRKR; CRKRS; cyclin dependent kinase 12; cyclin-dependent kinase 12; D11Ertd752e; H KIAA0904; hCDK12; KIAA0904; Pksc; protein kinase for splicing component

Filters

Less

2 results

Species

Expression System

Product Grade

Application

Price

Compare

2 results

Invitrogen

Human CDK12 (aa 1347-1468) Control Fragment Recombinant Protein

Invitrogen

Human CDK12 (aa 1347-1468) Control Fragment Recombinant Protein

Species

Human

Expression System

E. coli

Product Grade

Research Use Only

Application

Ctrl BLOCK

Price

Cat # RP-89808

100 µL

Invitrogen

Human CDK12 (aa 418-500) Control Fragment Recombinant Protein

Invitrogen

Human CDK12 (aa 418-500) Control Fragment Recombinant Protein

Species

Human

Expression System

E. coli

Product Grade

Research Use Only

Application

Ctrl BLOCK

Price

Cat # RP-109339

100 µL

Custom Antibody Service

Searching for an antibody we don't offer? We make custom antibodies for specific targets, species and applications.

More than 18,000 custom antibodies created so far.

Talk to a specialist now

CDK12 Proteins

Protein Information

Synonyms

Custom Antibody Service

We're here to help

Your items have has been added!