CDC42EP3 Proteins

Protein Information

CDC42, a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to, and negatively regulate the function of, CDC42. This protein can interact with CDC42, as well as with the ras homolog gene family, member Q (ARHQ/TC10). Expression of this protein in fibroblasts has been shown to induce pseudopodia formation.

Synonyms

3200001F04Rik; AA986861; Binder of Rho GTPases 2; Borg2; CDC42 effector protein (Rho GTPase binding) 3; CDC42 effector protein 3; Cdc42ep3; CEP3; CRIB-containing BORG2 protein; MSE55-related Cdc42-binding protein; MSE55-related protein; UB1