CD200 Proteins

CD200 recombinant proteins are available for Human and Mouse. These Protein have been validated for use in the following applications: ELISA, Immunohistochemistry, Western Blot and Functional Assay. These proteins are expressed in CHO cells and HEK293 cells. Available Product Grades: RUO.... CD200 recombinant proteins are available for Human and Mouse. These Protein have been validated for use in the following applications: ELISA, Immunohistochemistry, Western Blot and Functional Assay. These proteins are expressed in CHO cells and HEK293 cells. Available Product Grades: RUO. Our Gibco brand includes SKUs from PeproTech™,... CD200 recombinant proteins are available for Human and Mouse. These Protein have been validated for use in the following applications: ELISA, Immunohistochemistry, Western Blot and Functional Assay. These proteins are expressed in CHO cells and HEK293 cells. Available Product Grades: RUO. Our Gibco brand includes SKUs from PeproTech™, acquired by Thermo Fisher Scientific. Browse all 5 proteins, including biologically active options. Not finding the exact protein, grade or size needed? Contact us to discuss your specific application and product needs.... CD200 recombinant proteins are available for Human and Mouse. These Protein have been validated for use in the following applications: ELISA, Immunohistochemistry, Western Blot and Functional Assay. These proteins are expressed in CHO cells and HEK293 cells. Available Product Grades: RUO. Our Gibco brand includes SKUs from PeproTech™, acquired by Thermo Fisher Scientific. Browse all 5 proteins, including biologically active options. Not finding the exact protein, grade or size needed? Contact us to discuss your specific application and product needs.

Protein Information

CD200 is a type-1 membrane glycoprotein in the immunoglobulin superfamily, featuring two immunoglobulin domains. It is widely expressed on various cells, including B and T cells, keratinocytes, nerve cells, follicular dendritic cells, ovarian cells, and trophoblasts. CD200 interacts with CD200R on myeloid cells, inhibiting macrophage activation, reducing IL-6 production, and attenuating lymphocyte activation. It also prevents mast cell degranulation and decreases TNF-alpha and IL-13 secretion, playing a role in immune regulation and maternal tolerance. Homologues of CD200 are found in herpesviruses and poxviruses, indicating a conserved immune modulation function. CD200 has multiple alternatively spliced transcript variants, contributing to its functional diversity. Diseases linked to CD200 dysfunction include Mantle Cell Lymphoma and Primary Hypertrophic Osteoarthropathy, highlighting its importance in health and disease.

Synonyms

antigen identified by monoclonal antibody MRC OX-2; CD200; CD200 antigen; CD200 molecule; cell surface protein (thymocyte antigen identified by monoclonal antibody MRC-OX2); Cspmo2; MOX1; MOX2; MRC; MRC OX-2 antigen; MRCOX2; My033; OX2; OX-2; OX-2 membrane glycoprotein

CD200 Proteins

Protein Information

Synonyms

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