CCL27 Proteins

Protein Information

CCL27 gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The protein encoded by this gene is chemotactic for skin-associated memory T lymphocytes. This cytokine may also play a role in mediating homing of lymphocytes to cutaneous sites. It specifically binds to chemokine receptor 10 (CCR10). Studies of a similar murine protein indicate that these protein-receptor interactions have a pivotal role in T cell-mediated skin inflammation.

Synonyms

ALP; AW558992; CC chemokine ILC; C-C motif chemokine 27; C-C motif chemokine ligand 27; Ccl27; Ccl27a; chemokine (C-C motif) ligand 27; chemokine (C-C motif) ligand 27A; CTACK; CTAK; cutaneous T-cell attracting chemokine; cutaneous T-cell-attracting chemokine; ESkine; IL-11 R-alpha-locus chemokine; IL-11 Ralpha-locus chemokine; ILC; PESKY; SCYA27; Scya27a; Skinkine; skinskine; small inducible cytokine A27; small inducible cytokine A27a; small inducible cytokine subfamily A (Cys-Cys), member 27; small-inducible cytokine A27