CA150 Proteins

Protein Information

This gene encodes a nuclear protein that regulates transcriptional elongation and pre-mRNA splicing. The encoded protein interacts with the hyperphosphorylated C-terminal domain of RNA polymerase II via multiple FF domains, and with the pre-mRNA splicing factor SF1 via a WW domain. Alternative splicing results in multiple transcripts variants encoding different isoforms.

Synonyms

2410022J09Rik; 2900090C16Rik; AI428505; CA150; CA150b; coactivator of 150 kD; co-activator of 150 kDa; FBP 28; FBP23; FBP28; Formin-binding protein 28; MGC133200; p144; TAF2S; TATA box binding protein (TBP)-associated factor, RNA polymerase II, S, 150kD; TATA box-binding protein-associated factor 2S; TCERG1; transcription elongation regulator 1; transcription elongation regulator 1 (CA150); transcription factor CA150; transcription factor CA150b; Urn1