C19orf66 Proteins

C19orf66 Human recombinant proteins are validated for use in the following applications: Blocking Assay. Available Product Grades: RUO. Browse 1 protein. Not finding the exact protein, grade or size needed?... C19orf66 Human recombinant proteins are validated for use in the following applications: Blocking Assay. Available Product Grades: RUO. Browse 1 protein. Not finding the exact protein, grade or size needed? Contact us to discuss your specific application and product needs.... C19orf66 Human recombinant proteins are validated for use in the following applications: Blocking Assay. Available Product Grades: RUO. Browse 1 protein. Not finding the exact protein, grade or size needed? Contact us to discuss your specific application and product needs.... C19orf66 Human recombinant proteins are validated for use in the following applications: Blocking Assay. Available Product Grades: RUO. Browse 1 protein. Not finding the exact protein, grade or size needed? Contact us to discuss your specific application and product needs.

Protein Information

Inhibits programmed -1 ribosomal frameshifting (-1PRF) of a variety of mRNAs from viruses, such as HIV1, and cellular genes, such as PEG10. Interacts with the -1PRF signal of target mRNA and translating ribosomes and causes premature translation termination at the frameshifting site (PubMed:30682371). Regulates HIV1 GAG-POL expression by inhibiting -1PRF (PubMed:30682371). Exhibits antiviral activity against dengue virus (DENV) and can inhibit the replication of all DENV serotypes. May block the protein translation of DENV RNA via its association with cellular mRNA-binding proteins and viral RNA. Can also limit the replication of hepatitis C virus (HCV), West Nile virus (WNV), Chikungunya virus (CHIKV), herpes simplex virus type 1 (HHV-1) and human adenovirus (PubMed:26735137, PubMed:27974568). Binds nucleic acids with a higher affinity for ssRNA and ssDNA than for dsDNA (PubMed:27974568). [UniProt]

Synonyms

C19orf66; chromosome 19 open reading frame 66; FLJ11286; Interferon-regulated antiviral protein; IRAV; Repressor of yield of Dengue virus; repressor of yield of DENV; repressor of yield of DENV protein; RYDEN; SFL; SHFL; Shiftless antiviral inhibitor of ribosomal frameshifting protein; UPF0515 protein C19orf66

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Invitrogen

Human C19orf66 Control Fragment Recombinant Protein

Invitrogen

Human C19orf66 Control Fragment Recombinant Protein

Species

Human

Expression System

E. coli

Product Grade

Research Use Only

Application

Ctrl BLOCK

Price

Cat # RP-99101

100 µL

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C19orf66 Proteins

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