C19orf61 Proteins

Protein Information

This gene encodes a T cell adaptor protein, a class of intracellular molecules with modular domains capable of recruiting additional proteins but that exhibit no intrinsic enzymatic activity. The encoded protein contains a unique N-terminal region followed by a PH domain and C-terminal SH3 domain. Along with the adhesion and degranulation-promoting adaptor protein, the encoded protein plays a critical role in inside-out signaling by coupling T-cell antigen receptor stimulation to the activation of integrins.

Synonyms

1500002O20Rik; AI429693; C19orf61; F17127_1; HBMS; N28092; protein SMG9; Protein SMG-9; protein smg-9 homolog; RGD1309888; SMG9; smg-9 homolog, nonsense mediated mRNA decay factor (C. elegans); SMG9 nonsense mediated mRNA decay factor; SMG9, nonsense mediated mRNA decay factor