BHLHE40 Proteins

Protein Information

Differentiated embryo-chondrocyte expressed gene 1 (DEC1) is an important protein involved in embryonic cell differentiation, proliferation, and apoptosis. It has also recently been shown to be regulated by hypoxia. The loss of DEC1 expression may be an early event in the development of lung cancer, while DEC1 may be up-regulated by hypoxia in other cancers and in more extreme hypoxia it may have a role in cell death.

Synonyms

1-Dec; basic helix-loop-helix domain containing, class B, 2; basic helix-loop-helix domain containing, class B2; basic helix-loop-helix family member e40; basic helix-loop-helix family, member e40; bHLHb2; Bhlhe40; C130042M06Rik; Class B basic helix-loop-helix protein 2; class E basic helix-loop-helix protein 40; Clast5; CR8; cytokine response gene 8; DEC1; differentially expressed in chondrocytes 1; differentially expressed in chondrocytes protein 1; differentiated embryo chondrocyte expressed gene 1; E47 interaction protein 1; EIP1; eip1 (E47 interaction protein 1); enhancer-of split and hairy-related protein 2; enhancer-of-split and hairy-related protein 2; FLJ99214; HLHB2; Sharp2; SHARP-2; stimulated by retinoic acid 14; stimulated by retinoic acid gene 13 protein; Stra13; Stra14