ARMC10 Proteins

Protein Information

This gene encodes a protein that contains an armadillo repeat and transmembrane domain. The encoded protein decreases the transcriptional activity of the tumor suppressor protein p53 through direct interaction with the DNA-binding domain of p53, and may play a role in cell growth and survival. Upregulation of this gene may play a role in hepatocellular carcinoma. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 3.

Synonyms

2810037c14rik; armadillo repeat containing 10; armadillo repeat-containing protein 10; ARMC10; PNAS112; PNAS-112; PSEC0198; RGD1305915; specific splicing variant involved in hepatocarcinogenesis; splicing variant involved in hepatocarcinogenesis protein; SVH; SVH protein