APAF1 Proteins

APAF1 Human recombinant proteins are validated for use in the following applications: Blocking Assay. Available Product Grades: RUO. Browse 1 protein. Not finding the exact protein, grade or size needed?... APAF1 Human recombinant proteins are validated for use in the following applications: Blocking Assay. Available Product Grades: RUO. Browse 1 protein. Not finding the exact protein, grade or size needed? Contact us to discuss your specific application and product needs.... APAF1 Human recombinant proteins are validated for use in the following applications: Blocking Assay. Available Product Grades: RUO. Browse 1 protein. Not finding the exact protein, grade or size needed? Contact us to discuss your specific application and product needs.... APAF1 Human recombinant proteins are validated for use in the following applications: Blocking Assay. Available Product Grades: RUO. Browse 1 protein. Not finding the exact protein, grade or size needed? Contact us to discuss your specific application and product needs.

Protein Information

APAF1 gene encodes a cytoplasmic protein that initiates apoptosis. This protein contains several copies of the WD-40 domain, a caspase recruitment domain (CARD), and an ATPase domain (NB-ARC). Upon binding cytochrome c and dATP, this protein forms an oligomeric apoptosome. The apoptosome binds and cleaves caspase 9 preproprotein, releasing its mature, activated form. Activated caspase 9 stimulates the subsequent caspase cascade that commits the cell to apoptosis. Alternative splicing results in several transcript variants encoding different isoforms.

Synonyms

6230400I06Rik; Apaf1; APAF-1; Apaf1l; apoptotic peptidase activating factor 1; apoptotic protease activating factor 1; apoptotic protease-activating factor 1; CED4; DKFZp781B1145; fog; forebrain overgrowth; KIAA0413; mKIAA0413

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Invitrogen

Human APAF1 (aa 321-428) Control Fragment Recombinant Protein

Invitrogen

Human APAF1 (aa 321-428) Control Fragment Recombinant Protein

Species

Human

Expression System

E. coli

Product Grade

Research Use Only

Application

Ctrl BLOCK

Price

Cat # RP-95285

100 µL

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APAF1 Proteins

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