AP3S2 Proteins

Protein Information

AP3S2 (Adaptor Related Protein Complex 3 Subunit Sigma 2) is a Protein Coding gene. Among its related pathways are Lysosome. Gene Ontology (GO) annotations related to this gene include protein transporter activity. An important paralog of this gene is AP3S1. Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.

Synonyms

[s]3B; adapter-related protein complex 3 sigma-2 subunit; adapter-related protein complex 3 subunit sigma-2; adaptor complex sigma3B; adaptor related protein complex 3 sigma 2 subunit; adaptor related protein complex 3, sigma 2 subunit; adaptor-related protein complex 3 subunit sigma-2; adaptor-related protein complex 3, sigma 2 subunit; adaptor-related protein complex AP-3, sigma 2 subunit; AP-3 complex sigma-3B subunit; AP-3 complex subunit sigma-2; AP-3 complex subunit sigma-3B; AP3S2; AP3S3; clathrin-associated/assembly/adaptor protein, small 4, 22-kD; FLJ35955; sigma 3B; sigma3b; sigma-3B-adaptin; Sigma3B-adaptin; Sigma-adaptin 3b