ALG3 Proteins

Protein Information

This gene encodes a member of the ALG3 family. The encoded protein catalyzes the addition of the first dol-P-Man derived mannose in an alpha 1,3 linkage to Man5GlcNAc2-PP-Dol. Defects in this gene have been associated with congenital disorder of glycosylation type Id (CDG-Id) characterized by abnormal N-glycosylation. Multiple transcript variants encoding different isoforms have been found for this gene.

Synonyms

ALG3; ALG3, alpha-1,3- mannosyltransferase; asparagine-linked glycosylation 3 homolog (S. cerevisiae, alpha-1,3-mannosyltransferase); asparagine-linked glycosylation 3 homolog (yeast, alpha-1,3-mannosyltransferase); asparagine-linked glycosylation 3, alpha-1,3- mannosyltransferase homolog; asparagine-linked glycosylation protein 3 homolog; carbohydrate deficient glycoprotein syndrome type IV; CDG1D; CDGS4; CDGS6; D16Ertd36e; dolichyl-phosphate-mannose--glycolipid alpha-mannosyltransferase; Dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichyl mannosyltransferase; dol-P-Man dependent alpha(1-3)-mannosyltransferase; dol-P-Man dependent alpha-1,3- mannosyltransferase; Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase; dol-P-Man:Man(5)GlcNAc(2)-PP-Dol3-mannosyltransferase; dol-P-Man-dependent alpha(1-3)-mannosyltransferase; not; Not56; NOT56L; Not56-like protein