AGPS Proteins

Protein Information

This gene is a member of the FAD-binding oxidoreductase/transferase type 4 family. It encodes a protein that catalyzes the second step of ether lipid biosynthesis in which acyl-dihydroxyacetonephosphate (DHAP) is converted to alkyl-DHAP by the addition of a long chain alcohol and the removal of a long-chain acid anion. The protein is localized to the inner aspect of the peroxisomal membrane and requires FAD as a cofactor. Mutations in this gene have been associated with rhizomelic chondrodysplasia punctata, type 3 and Zellweger syndrome.

Synonyms

5832437L22; 9930035G10Rik; AAG5; Adaps; Adap-s; ADAS; Adhaps; Adps; Ads; Aging-associated gene 5 protein; aging-associated protein 5; AGPS; Aldhpsy; Alkyl-DHAP synthase; alkyldihydroxyacetone phosphate synthase; alkyl-dihydroxyacetonephosphate synthase; alkyldihydroxyacetonephosphate synthase, peroxisomal; alkylglycerone phosphate synthase; alkylglycerone phosphate synthase-like; Alkylglycerone-phosphate synthase; AW123847; bs2; RCDP3