ABI1 Proteins

Protein Information

This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The nucleolar protein encoded by this gene interacts in a hormone-dependent manner with nuclear receptors, and represses their transcriptional activity. Alternative splice variants that encode different isoforms have been found for this gene.

Synonyms

Abelson interactor 1; ABI1; Abi-1; Abl interactor 1; abl-binding protein 4; AblBP4; abl-interactor 1; Abl-interactor protein 1 long; Ablphilin-1; e3B1; EL2; eps8 binding protein; eps8 binding protein (e3B1), alternatively spliced; eps8 SH3 domain-binding protein; Eps8-binding protein; HPP; HS3; interactor protein AblBP4; NAP1; nap1 binding protein; Nap1-binding protein; Nap1BP; spectrin SH3 domain binding protein 1; spectrin SH3 domain-binding protein 1; SPH3; SPTA; SSH3BP; Ssh3bp1