A1CF Proteins

Protein Information

Mammalian apolipoprotein B mRNA undergoes site-specific Cto U deamination, which is mediated by a multi-component enzyme complex containing a minimal core composed of APOBEC-1 and acomplementation factor encoded by this gene. The gene product has three non-identical RNA recognition motifs and belongs to the hnRNPR family of RNA-binding proteins. It has been proposed that this complementation factor functions as an RNA-binding subunit and docks APOBEC-1 to deaminate the upstream cytidine. Studies suggest that the protein may also be involved in other RNA editing or RNA processing events.

Synonyms

1810073H04Rik; A1cf; A1cft; ACF; ACF64; ACF65; apo-B RNA editing protein; Apobec-1; APOBEC1 complementation factor; apobec-1 complementation factor; apobec-1 complementation factor (ACF) (ASP); Apobec-1 complementation factor APOBEC-1 stimulating protein; Apobec-1 complementation factor, APOBEC-1 stimulating protein; APOBEC1 complementation factort; APOBEC-1 stimulating protein; APOBEC1CF; APOBEC1-stimulating protein; ASP; MGC163391; RP11-564C4.2